Advanced Synthesis Platform2020-05-06T15:59:14+00:00

Advanced Synthesis Platform

Our experience with complex chemical transformations on both small and large scale spans decades. Our laboratories are equipped to support the manufacture of pharmaceutical products across a wide range of processes covering carbon-carbon and carbon-heteratom bond formation, chiral chemistry, REDOX reactions and protecting group chemistry. We have extensive on-scale experience with highly telescoped processes.

We offer the following Process Development services:

  • Lactamisation
  • Mixed anhydride formation
  • Nucleophilic aromatic substitution
  • Amidation
  • SN2 epoxide ring-opening
  • Buchwald-Hartwig amination
  • Classical resolution
  • Sharpless asymmetric epxoidation
  • Oxygen-sensitive coupling
  • Heck and Vielsmeier coupling
  • Esterification
  • Hydrogenation
  • Red-Al reduction
  • Glycoside reduction
  • Peroxide and hypochlorite oxidation
  • Fleming oxidation
  • Staudinger reduction
  • Dehydration of amide to nitrile
  • Allylation
  • Halogenation
  • Protecting group chemistry (acetalisation, orthoester formation, de-Bocylation)

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